Mat2a | methionine adenosyltransferase 2A
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Nervous system Hematopoietic system Behavior/neurological Mortality/aging
15 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:76Adult tissues
25Embryo tissues
| decreased granulocyte number | 1 supporting dataset | Mat2atm1a(EUCOMM)Hmgu | heterozygote | Early adult | 5.18x10-5 | ||
| increased startle reflex | 4 supporting datasets | Mat2atm1a(EUCOMM)Hmgu | heterozygote | Early adult | 3.62x10-9 | ||
| decreased prepulse inhibition | 4 supporting datasets | Mat2atm1a(EUCOMM)Hmgu | heterozygote | Early adult | 6.72x10-11 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Mat2atm1a(EUCOMM)Hmgu | heterozygote | Early adult | 2.1x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Mat2atm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| increased circulating triglyceride level | 1 supporting dataset | Mat2atm1a(EUCOMM)Hmgu | heterozygote | Early adult | 1.89x10-5 |
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External links
No external links available for Mat2a.
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| Mat2atm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Mat2atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Mat2atm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |