Gatad2b | GATA zinc finger domain containing 2B

GeneMGI:2443225Synonyms: C430014D17Rik, p66beta

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased monocyte cell number	1 supporting dataset	Gatad2b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.02x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Gatad2b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.93x10^-5
decreased locomotor activity	1 supporting dataset	Gatad2b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.01x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Gatad2b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Gatad2b^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.67x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gatad2b.

Associated images

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Histopathology

There is no histopathology data found for Gatad2b.

IMPC related publications

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External links

No external links available for Gatad2b.

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*Gatad2b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gatad2b^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gatad2b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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