Ces2e | carboxylesterase 2E

GeneMGI:2443170Synonyms: 9030624L02Rik, Ces5

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetCes2eem1(IMPC)MarchomozygoteEarly adult1.49x10-10 
increased basophil cell number2 supporting datasetsCes2eem1(IMPC)MarchomozygoteEarly adult1.56x10-61 
decreased hematocrit1 supporting datasetCes2eem1(IMPC)MarchomozygoteEarly adult1.76x10-5 
increased circulating creatinine level1 supporting datasetCes2eem1(IMPC)MarchomozygoteEarly adult2.39x10-7 
increased eosinophil cell number2 supporting datasetsCes2eem1(IMPC)MarchomozygoteEarly adult1.71x10-36 
thrombocytopenia1 supporting datasetCes2eem1(IMPC)MarchomozygoteEarly adult6.08x10-6 
decreased hemoglobin content1 supporting datasetCes2eem1(IMPC)MarchomozygoteEarly adult2.69x10-5 
decreased erythrocyte cell number1 supporting datasetCes2eem1(IMPC)MarchomozygoteEarly adult5.05x10-6 
decreased mean corpuscular volume1 supporting datasetCes2eem1(IMPC)MarchomozygoteEarly adult1.38x10-16 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ces2eem1(IMPC)MarcDeletionmouse
Ces2etm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ces2etm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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