Trim65 | tripartite motif-containing 65

GeneMGI:2442815Synonyms: 4732463G12Rik

Physiological systems

18 / 24 physiological systems tested

18 No significant impact

6 Not tested

Gene metrics:0Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a100% (2/2)0.19% (1/533)
blood vesselheterozygoten/a0% (0/2)0% (0/173)
boneheterozygoten/a0% (0/2)0% (0/394)
brainheterozygoten/a100% (2/2)0.86% (5/579)
brainstemheterozygoten/a0% (0/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
cerebral cortexheterozygoten/a0% (0/2)0.41% (2/491)
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Human diseases caused by Trim65 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Trim65tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Trim65tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Trim65tm43706(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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