Mical3 | microtubule associated monooxygenase, calponin and LIM domain containing 3
Physiological systems
17 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Pigmentation Immune system Integument Hearing/vestibular/ear Hematopoietic system Behavior/neurological
11 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean corpuscular hemoglobin | 1 supporting dataset | Mical3em1(IMPC)J | homozygote | Early adult | 1.99x10-7 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Mical3em1(IMPC)J | homozygote | Early adult | 9.27x10-8 | ||
| hyperactivity | 2 supporting datasets | Mical3em1(IMPC)J | homozygote | Early adult | 9x10-5 | ||
| increased leukocyte cell number | 1 supporting dataset | Mical3em1(IMPC)J | homozygote | Early adult | 3.1x10-5 | ||
| abnormal vocalization | 1 supporting dataset | Mical3em1(IMPC)J | homozygote | Early adult | 9.21x10-7 |
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Human diseases caused by Mical3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Mical3.
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| Mical3em1(IMPC)J | Exon Deletion | | mouse |