Tspyl5 | testis-specific protein, Y-encoded-like 5
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Behavior/neurological Cardiovascular system
14 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal retina blood vessel morphology | 1 supporting dataset | Tspyl5em1(IMPC)Tcp | homozygote | Early adult | 2.24x10-5 | ||
| abnormal iris morphology | 1 supporting dataset | Tspyl5em1(IMPC)Tcp | homozygote | Early adult | 5.08x10-5 | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Tspyl5em1(IMPC)Tcp | homozygote | Early adult | 1.81x10-5 | ||
| impaired pupillary reflex | 1 supporting dataset | Tspyl5em1(IMPC)Tcp | homozygote | Early adult | 9.02x10-5 |
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Human diseases caused by Tspyl5 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tspyl5.
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| Tspyl5em1(IMPC)Tcp | Intra-exon deletion | | mouse |