Peak1 | pseudopodium-enriched atypical kinase 1

GeneMGI:2442366Synonyms: C230081A13Rik, 1110049L02Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal cholesterol homeostasis1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult2.15x10-11 
decreased blood urea nitrogen level1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult9.44x10-5 
increased lean body mass1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult7.63x10-7 
decreased circulating cholesterol level1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult2.59x10-8 
decreased circulating serum albumin level1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult1.59x10-5 
decreased circulating calcium level1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult3.26x10-5 
increased startle reflex1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult6.21x10-10 
decreased circulating total protein level1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult2.78x10-6 
thrombocytopenia1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult7.17x10-5 
decreased circulating HDL cholesterol level1 supporting datasetPeak1em1(IMPC)JhomozygoteEarly adult5.47x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Peak1em1(IMPC)JExon Deletionmouse

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