Tlk1 | tousled-like kinase 1
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system
16 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| increased circulating bilirubin level | 1 supporting dataset | Tlk1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.17x10-6 | ||
| increased circulating phosphate level | 1 supporting dataset | Tlk1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.43x10-6 | ||
| impaired glucose tolerance | 1 supporting dataset | Tlk1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.07x10-5 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Tlk1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.82x10-7 | ||
| thrombocytopenia | 1 supporting dataset | Tlk1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.51x10-6 | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Tlk1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.38x10-10 |
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External links
No external links available for Tlk1.
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| Tlk1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tlk1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Tlk1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |