Mrgprb2 | MAS-related GPR, member B2
Physiological systems
20 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Renal/urinary system
11 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal skin morphology | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| decreased exploration in new environment | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Early adult | 4.5x10-7 | ||
| polycystic kidney | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| small kidney | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| decreased exploration in new environment | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Late adult | 5.29x10-5 | ||
| small spleen | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| decreased exploration in new environment | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Middle aged adult | 1.55x10-5 | ||
| small adrenal glands | 1 supporting dataset | Mrgprb2em1(IMPC)Tcp | homozygote | Late adult | N/A * |
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Human diseases caused by Mrgprb2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Mrgprb2.
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| Mrgprb2em1(IMPC)Tcp | Intra-exon deletion | | mouse |