Lrrtm2 | leucine rich repeat transmembrane neuronal 2

GeneMGI:2389174Synonyms: C630011A14Rik

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Liver/biliary system Respiratory system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

10 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



urinary bladder obstruction	1 supporting dataset	Lrrtm2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	2 supporting datasets	Lrrtm2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Lrrtm2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Lrrtm2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Lrrtm2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Lrrtm2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Lrrtm2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged kidney	1 supporting dataset	Lrrtm2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Lrrtm2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
hyperactivity	1 supporting dataset	Lrrtm2^em1(IMPC)Mbp	homozygote	Early adult	5.43x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lrrtm2.

Associated images

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Histopathology

There is no histopathology data found for Lrrtm2.

IMPC related publications

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External links

No external links available for Lrrtm2.

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*Lrrtm2^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Lrrtm2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Lrrtm2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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