Zc3h12a | zinc finger CCCH type containing 12A

GeneMGI:2385891Synonyms: Mcpip1

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetZc3h12atm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased circulating lipase level1 supporting datasetZc3h12atm1b(EUCOMM)HmguheterozygoteEarly adult3.85x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zc3h12atm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Zc3h12atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Zc3h12atm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Zc3h12atm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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