Zc3h12a | zinc finger CCCH type containing 12A
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
18 No significant impact
4 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Zc3h12atm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| increased circulating lipase level | 1 supporting dataset | Zc3h12atm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.85x10-14 |
| | | | | | | | | | |
Human diseases caused by Zc3h12a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Zc3h12a.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Zc3h12atm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Zc3h12atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Zc3h12atm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Zc3h12atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |