Ddx27 | DEAD box helicase 27

GeneMGI:2385884Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 27

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Ddx27^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Ddx27^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased granulocyte number	1 supporting dataset	Ddx27^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	1.74x10^-5
abnormal behavior	3 supporting datasets	Ddx27^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	6.36x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ddx27.

Associated images

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Histopathology

There is no histopathology data found for Ddx27.

IMPC related publications

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External links

No external links available for Ddx27.

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*Ddx27^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ddx27^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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