Tcaf2 | TRPM8 channel-associated factor 2
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Growth/size/body region Muscle Vision/eye Hematopoietic system
16 No significant impact
2 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged thymus | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal skeletal muscle morphology | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| anophthalmia | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal thymus morphology | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| increased erythrocyte cell number | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | 8.45x10-6 | ||
| abnormal eye morphology | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Tcaf2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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Human diseases caused by Tcaf2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tcaf2.
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