Cdk5rap2 | CDK5 regulatory subunit associated protein 2

GeneMGI:2384875Synonyms: 2900018K03Rik, an

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Skeleton Craniofacial

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased body weight	4 supporting datasets	Cdk5rap2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.38x10^-7
abnormal head morphology	1 supporting dataset	Cdk5rap2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.15x10^-5
abnormal cranium morphology	1 supporting dataset	Cdk5rap2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.6x10^-6
increased mean corpuscular hemoglobin	1 supporting dataset	Cdk5rap2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.32x10^-9
decreased leukocyte cell number	1 supporting dataset	Cdk5rap2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.37x10^-8
increased mean corpuscular volume	1 supporting dataset	Cdk5rap2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.43x10^-14
decreased erythrocyte cell number	1 supporting dataset	Cdk5rap2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.38x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cdk5rap2.

Associated images

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Histopathology

There is no histopathology data found for Cdk5rap2.

IMPC related publications

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External links

No external links available for Cdk5rap2.

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*Cdk5rap2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

My Genes