Tnpo2 | transportin 2 (importin 3, karyopherin beta 2b)
Physiological systems
12 / 24 physiological systems tested
12 No significant impact
12 Not tested
Data collections
Gene metrics:0Significant phenotypes
1Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| adrenal gland | heterozygote | Wholemount images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Wholemount images | 100% (2/2) | 0.19% (1/533) |
| bone | heterozygote | Wholemount images | 100% (2/2) | 0% (0/394) |
| brain | heterozygote | Wholemount images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Wholemount images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | Wholemount images | 100% (2/2) | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/2) | 7.75% (22/284) |
| cerebellum | heterozygote | Wholemount images | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Wholemount images | 100% (2/2) | 0.41% (2/491) |
Human diseases caused by Tnpo2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tnpo2.
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| Tnpo2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tnpo2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Tnpo2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |