Prpsap2 | phosphoribosyl pyrophosphate synthetase-associated protein 2

GeneMGI:2384838Synonyms: A230054F23Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex2 supporting datasetsPrpsap2tm1a(EUCOMM)WtsihomozygoteEarly adult5.03x10-9 
decreased CD8-positive, alpha-beta T cell number1 supporting datasetPrpsap2tm1a(EUCOMM)WtsihomozygoteEarly adult4.23x10-5 
abnormal metabolism1 supporting datasetPrpsap2tm1a(EUCOMM)WtsihomozygoteEarly adult1.66x10-5 
abnormal behavior1 supporting datasetPrpsap2tm1a(EUCOMM)WtsihomozygoteEarly adult2.34x10-5 
short tibia1 supporting datasetPrpsap2tm1a(EUCOMM)WtsihomozygoteEarly adult7.26x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prpsap2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Prpsap2tm297(pL1L2_GT2_DelLacZ_bsd)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Prpsap2tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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