Pfkfb3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

GeneMGI:2181202Synonyms: E330010H22Rik, uPFK-2

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Skeleton

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



abnormal bone structure	1 supporting dataset	Pfkfb3^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.51x10^-5
decreased bone mineral density	1 supporting dataset	Pfkfb3^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	7.96x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pfkfb3.

Associated images

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Histopathology

There is no histopathology data found for Pfkfb3.

IMPC related publications

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External links

No external links available for Pfkfb3.

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*Pfkfb3^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Pfkfb3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pfkfb3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pfkfb3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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