Trim37 | tripartite motif-containing 37

GeneMGI:2153072Synonyms: MUL, TEF3, +2 more

Physiological systems

18 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

7 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased grip strength	2 supporting datasets	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	7.61x10^-8
increased fasting circulating glucose level	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	5.33x10^-5
decreased lymphocyte cell number	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	1.08x10^-7
decreased bone mineral content	2 supporting datasets	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	2x10^-19
abnormal bone structure	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	1.32x10^-6
decreased leukocyte cell number	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	5.52x10^-7
male infertility	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	N/A ^*
improved glucose tolerance	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	1.09x10^-13
decreased bone mineral density	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	1.28x10^-13
increased basophil cell number	1 supporting dataset	Trim37^{em1(IMPC)Marc}	homozygote	Early adult	4.99x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trim37.

Associated images

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Histopathology

There is no histopathology data found for Trim37.

IMPC related publications

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External links

No external links available for Trim37.

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*Trim37^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Trim37^{tm55(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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