Nexmif | neurite extension and migration factor
Physiological systems
17 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Integument Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Renal/urinary system
7 No significant impact
7 Not tested
Data collections
Gene metrics:21Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| male infertility | 1 supporting dataset | Nexmifem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased lean body mass | 1 supporting dataset | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | 4.18x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | 0 | ||
| abnormal sternum morphology | 1 supporting dataset | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | N/A * | ||
| increased red blood cell distribution width | 1 supporting dataset | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | 4.44x10-16 | ||
| hyperactivity | 8 supporting datasets | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | 0 | ||
| decreased bone mineral content | 1 supporting dataset | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | 2.17x10-5 | ||
| increased circulating triglyceride level | 1 supporting dataset | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | 3.61x10-5 | ||
| enlarged urinary bladder | 1 supporting dataset | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | N/A * | ||
| increased eosinophil cell number | 2 supporting datasets | Nexmifem1(IMPC)Tcp | hemizygote | Early adult | 8.47x10-9 |
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Human diseases caused by Nexmif mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Nexmif.
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| Nexmifem1(IMPC)Tcp | Intra-exon deletion | | mouse |
| Nexmiftm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |