Atg4a | autophagy related 4A, cysteine peptidase

GeneMGI:2147903Synonyms: autophagin 2, Autl2, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased total body fat amount	2 supporting datasets	Atg4a^{em2(IMPC)Marc}	homozygote	Early adult	3.23x10^-8
increased basophil cell number	2 supporting datasets	Atg4a^{em2(IMPC)Marc}	homozygote	Early adult	1.11x10^-22
decreased bone mineral content	2 supporting datasets	Atg4a^{em2(IMPC)Marc}	homozygote	Early adult	1.8x10^-8
increased eosinophil cell number	2 supporting datasets	Atg4a^{em2(IMPC)Marc}	homozygote	Early adult	1.97x10^-15
decreased lean body mass	1 supporting dataset	Atg4a^{em2(IMPC)Marc}	homozygote	Early adult	2.84x10^-7
decreased bone mineral density	1 supporting dataset	Atg4a^{em2(IMPC)Marc}	homozygote	Early adult	6.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atg4a.

Associated images

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Histopathology

There is no histopathology data found for Atg4a.

IMPC related publications

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External links

No external links available for Atg4a.

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*Atg4a^{em2(IMPC)Marc}*	Deletion	‌	mouse

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