AW112010 | expressed sequence AW112010

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Hematopoietic system

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetAW112010em1(IMPC)MarchomozygoteEarly adult4.75x10-10 
decreased mean corpuscular volume1 supporting datasetAW112010em1(IMPC)MarchomozygoteEarly adult9.7x10-17 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

Human diseases caused by AW112010 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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AW112010em1(IMPC)MarcDeletionmouse
AW112010em1(IMPC)WtsiDeletionmouse
AW112010tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
AW112010tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
AW112010tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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