Cdk20 | cyclin dependent kinase 20

GeneMGI:2145349Synonyms: Ccrk, 4932702G04Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Embryo Growth/size/body region Digestive/alimentary Limbs/digits/tail Vision/eye Craniofacial Mortality/aging

13 No significant impact

4 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal body wall morphology1 supporting datasetCdk20em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal embryo size1 supporting datasetCdk20em1(IMPC)BayhomozygoteE18.5N/A * 
polydactyly1 supporting datasetCdk20em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal facial morphology2 supporting datasetsCdk20em1(IMPC)BayhomozygoteE18.5N/A * 
cleft palate1 supporting datasetCdk20em1(IMPC)BayhomozygoteE18.5N/A * 
facial cleft1 supporting datasetCdk20em1(IMPC)BayhomozygoteE18.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsCdk20em1(IMPC)BayhomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetCdk20em1(IMPC)BayhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdk20em1(IMPC)BayExon Deletionmouse
Cdk20tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cdk20tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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