Slc25a47 | solute carrier family 25, member 47
GeneMGI:2144766
Physiological systems
18 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Mortality/aging
17 No significant impact
6 Not tested
Data collections
Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Slc25a47tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 100% (1/1) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/1) | 0.19% (1/533) |
| bone | heterozygote | n/a | 0% (0/1) | 0% (0/394) |
| brain | heterozygote | n/a | 0% (0/1) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/1) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/1) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/1) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 0% (0/1) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/1) | 0.41% (2/491) |
| esophagus | heterozygote | n/a | 0% (0/1) | 1.67% (7/419) |
Human diseases caused by Slc25a47 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Slc25a47.
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| Slc25a47tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Slc25a47tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Slc25a47tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Slc25a47tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Slc25a47tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |