Cog8 | component of oligomeric golgi complex 8

GeneMGI:2142885Synonyms: C87832

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating bilirubin level1 supporting datasetCog8em1(IMPC)JheterozygoteEarly adult1.53x10-7 
preweaning lethality, complete penetrance1 supporting datasetCog8em1(IMPC)JhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetCog8em1(IMPC)JhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Cog8em1(IMPC)JExon Deletionmouse
Cog8tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cog8tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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