Crtc1 | CREB regulated transcription coactivator 1

GeneMGI:2142523Synonyms: Mect1, TORC1

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Nervous system Hematopoietic system Behavior/neurological Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased prepulse inhibition	3 supporting datasets	Crtc1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.42x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Crtc1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased IgG2b level	1 supporting dataset	Crtc1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.09x10^-5
increased startle reflex	1 supporting dataset	Crtc1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.29x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Crtc1.

Associated images

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Histopathology

There is no histopathology data found for Crtc1.

IMPC related publications

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External links

No external links available for Crtc1.

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*Crtc1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

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