Usb1 | U6 snRNA biogenesis 1
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
17 No significant impact
5 Not tested
Data collections
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Usb1em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Usb1em1(IMPC)Bay | homozygote | E12.5 | N/A * | ||
| edema | 1 supporting dataset | Usb1em1(IMPC)Bay | homozygote | E9.5 | N/A * |
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Human diseases caused by Usb1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Usb1.
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| Usb1em1(IMPC)Bay | Exon Deletion | | mouse |
| Usb1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Usb1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Usb1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |