Phrf1 | PHD and ring finger domains 1

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Hematopoietic system Skeleton Cardiovascular system Renal/urinary system

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



enlarged salivary gland	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal salivary gland morphology	2 supporting datasets	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
small spleen	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
small uterus	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
enlarged lymph nodes	2 supporting datasets	Phrf1^em1(IMPC)Tcp	homozygote	Late adult	N/A ^*
increased circulating triglyceride level	1 supporting dataset	Phrf1^em1(IMPC)Tcp	homozygote	Early adult	5.97x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Phrf1.

Associated images

2 images

Electrocardiogram (ECG)

Waveform Image

144 images

Eye Morphology

Images Ophthalmoscopy

2 images

Eye Morphology

Images Slit Lamp

8 images

Gross Pathology and Tissue Collection

Images

1 images

Histopathology

Images

10 images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 images

X-ray

XRay Images Skull Lateral Orientation

10 images

X-ray

XRay Images Whole Body Dorso Ventral

10 images

X-ray

XRay Images Whole Body Lateral Orientation

Histopathology

This gene doesn't have any significant Histopathology hits. Click here to see the raw data

IMPC related publications

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External links

No external links available for Phrf1.

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*Phrf1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse

My Genes

Phrf1 | PHD and ring finger domains 1

Physiological systems

11 Significantly impacted by the knock-out

9 No significant impact

4 Not tested

Data collections

Phenotypes

lacZ Expression

Associated images

Electrocardiogram (ECG)

Eye Morphology

Eye Morphology

Gross Pathology and Tissue Collection

Histopathology

X-ray

X-ray

X-ray

X-ray

Histopathology

IMPC related publications

External links

Order Mouse and ES Cells

The IMPC Newsletter

Access Data Release 22.1 Data