Mapre3 | microtubule-associated protein, RP/EB family, member 3
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Adipose tissue Hematopoietic system Mortality/aging
16 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased leukocyte cell number | 1 supporting dataset | Mapre3tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.65x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Mapre3tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Mapre3tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 9.95x10-5 |
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Human diseases caused by Mapre3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Mapre3.
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| Mapre3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Mapre3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Mapre3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |