Mapre3 | microtubule-associated protein, RP/EB family, member 3

GeneMGI:2140967Synonyms: EB3

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Adipose tissue Hematopoietic system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased leukocyte cell number1 supporting datasetMapre3tm1a(EUCOMM)WtsiheterozygoteEarly adult2.65x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetMapre3tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased total body fat amount1 supporting datasetMapre3tm1a(EUCOMM)WtsiheterozygoteEarly adult9.95x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mapre3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Mapre3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Mapre3tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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