Clca2 | chloride channel accessory 2

GeneMGI:2139758Synonyms: Clca5

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Vision/eye Renal/urinary system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal testis morphology	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	5.99x10^-5
cataract	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	6.35x10^-5
abnormal retina morphology	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	3.03x10^-5
small kidney	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	4.82x10^-6
abnormal kidney morphology	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Clca2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clca2.

Associated images

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Histopathology

There is no histopathology data found for Clca2.

IMPC related publications

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External links

No external links available for Clca2.

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*Clca2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Clca2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Clca2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Clca2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Clca2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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