Pkmyt1 | protein kinase, membrane associated tyrosine/threonine 1
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Integument Embryo Nervous system Liver/biliary system Behavior/neurological Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased grip strength | 1 supporting dataset | Pkmyt1em1(IMPC)J | heterozygote | Early adult | 1.95x10-6 | ||
prenatal lethality prior to heart atrial septation | 1 supporting dataset | Pkmyt1em1(IMPC)J | homozygote | E15.5 | N/A * | ||
pallor | 1 supporting dataset | Pkmyt1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
abnormal neural tube closure | 1 supporting dataset | Pkmyt1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
abnormal forebrain morphology | 1 supporting dataset | Pkmyt1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
abnormal vocalization | 1 supporting dataset | Pkmyt1em1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Pkmyt1em1(IMPC)J | homozygote | Early adult | N/A * | ||
pale liver | 1 supporting dataset | Pkmyt1em1(IMPC)J | homozygote | E12.5 | N/A * | ||
abnormal coat/ hair morphology | 1 supporting dataset | Pkmyt1em1(IMPC)J | heterozygote | Early adult | 2.71x10-5 |
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External links
No external links available for Pkmyt1.
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Pkmyt1em1(IMPC)J | Exon Deletion | | mouse |
Pkmyt1tm267248(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |