Trim16 | tripartite motif-containing 16

GeneMGI:2137356Synonyms: 9130006M08Rik, EBBP

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal sternum morphology1 supporting datasetTrim16em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetTrim16em1(IMPC)TcphomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetTrim16em1(IMPC)TcphomozygoteEarly adult3.22x10-6 
increased red blood cell distribution width1 supporting datasetTrim16em1(IMPC)TcphomozygoteEarly adult2.76x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Trim16 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Trim16em1(IMPC)TcpIntra-exon deletionmouse

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