Trim9 | tripartite motif-containing 9
Physiological systems
21 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Respiratory system Hematopoietic system Skeleton Renal/urinary system
11 No significant impact
3 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating sodium level | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | 7.96x10-7 | ||
| decreased effector memory T-helper cell number | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | 5.51x10-8 | ||
| decreased spleen weight | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | 1.59x10-8 | ||
| abnormal prostate gland morphology | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | 7.21x10-5 | ||
| abnormal lung morphology | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| small prostate gland | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged kidney | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal vertebral arch morphology | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | 5.74x10-9 | ||
| abnormal kidney morphology | 1 supporting dataset | Trim9em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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Human diseases caused by Trim9 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Trim9.
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| Trim9em1(IMPC)Ccpcz | Indel | | mouse |
| Trim9tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Trim9tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |