Sbk1 | SH3-binding kinase 1
GeneMGI:2135937
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Integument Vision/eye Mortality/aging
18 No significant impact
3 Not tested
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues
| decreased total retina thickness | 1 supporting dataset | Sbk1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.05x10-5 | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Sbk1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal coat appearance | 1 supporting dataset | Sbk1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.69x10-8 | ||
| abnormal eye anterior chamber depth | 1 supporting dataset | Sbk1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.49x10-9 | ||
| abnormal eye anterior chamber depth | 1 supporting dataset | Sbk1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 4.46x10-8 | ||
| abnormal skin coloration | 1 supporting dataset | Sbk1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.1x10-5 |
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External links
No external links available for Sbk1.
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| Sbk1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Sbk1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Sbk1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |