Sytl1 | synaptotagmin-like 1

GeneMGI:1933365Synonyms: PSGL-1, Slp1

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Pigmentation Integument Hematopoietic system Behavior/neurological

15 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:90Adult tissues
0Embryo tissues

Phenotypes

increased blood uric acid level1 supporting datasetSytl1tm1a(KOMP)WtsihomozygoteEarly adult6.41x10-6 
increased hematocrit1 supporting datasetSytl1tm1a(KOMP)WtsihomozygoteEarly adult3.04x10-5 
abnormal coat/hair pigmentation1 supporting datasetSytl1tm1a(KOMP)WtsihomozygoteEarly adult3.89x10-5 
increased leukocyte cell number1 supporting datasetSytl1tm1a(KOMP)WtsihomozygoteEarly adult7.16x10-5 
abnormal response to tactile stimuli1 supporting datasetSytl1tm1a(KOMP)WtsihomozygoteEarly adult5.17x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sytl1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Sytl1tm44240(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Sytl1tm44240(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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