Usp26 | ubiquitin specific peptidase 26

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased eosinophil cell number2 supporting datasetsUsp26em1(IMPC)MarchemizygoteEarly adult4.08x10-21 
increased basophil cell number2 supporting datasetsUsp26em1(IMPC)MarchemizygoteEarly adult7.84x10-21 
decreased locomotor activity2 supporting datasetsUsp26em1(IMPC)MarchemizygoteEarly adult6.56x10-6 
increased circulating triglyceride level1 supporting datasetUsp26em1(IMPC)MarchomozygoteEarly adult3.49x10-5 
increased basophil cell number1 supporting datasetUsp26em1(IMPC)MarchomozygoteEarly adult3.98x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Usp26em1(IMPC)MarcDeletionmouse
Usp26tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Usp26tm433063(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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