Ift122 | intraflagellar transport 122

GeneMGI:1932386Synonyms: C86139, sopb, +1 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



long tibia	1 supporting dataset	Ift122^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.49x10^-6
decreased locomotor activity	1 supporting dataset	Ift122^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.06x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Ift122^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.85x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Ift122^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Ift122^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.65x10^-7
abnormal behavior	1 supporting dataset	Ift122^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.52x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ift122.

Associated images

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Histopathology

There is no histopathology data found for Ift122.

IMPC related publications

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External links

No external links available for Ift122.

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*Ift122^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ift122^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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