Selenok | selenoprotein K

GeneMGI:1931466Synonyms: Selk, 30kDa, +1 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear Hematopoietic system Skeleton

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased lean body mass	1 supporting dataset	Selenok^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.01x10^-5
decreased circulating magnesium level	1 supporting dataset	Selenok^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.87x10^-5
increased total body fat amount	1 supporting dataset	Selenok^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.88x10^-5
abnormal auditory brainstem response	1 supporting dataset	Selenok^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.22x10^-8
abnormal vertebral arch morphology	1 supporting dataset	Selenok^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.87x10^-5
abnormal spine curvature	1 supporting dataset	Selenok^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.04x10^-5
decreased mean platelet volume	1 supporting dataset	Selenok^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Selenok.

Associated images

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Histopathology

There is no histopathology data found for Selenok.

IMPC related publications

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External links

No external links available for Selenok.

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*Selenok^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Selenok^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Selenok^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Selenok^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Selenok^{tm44541(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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