Sap30 | sin3 associated polypeptide
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean corpuscular hemoglobin | 1 supporting dataset | Sap30em1(IMPC)J | homozygote | Early adult | 3.75x10-36 | ||
| increased mean corpuscular volume | 1 supporting dataset | Sap30em1(IMPC)J | homozygote | Early adult | 6.46x10-13 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Sap30em1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased circulating glucose level | 1 supporting dataset | Sap30em1(IMPC)J | homozygote | Early adult | 1.02x10-7 |
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Human diseases caused by Sap30 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Sap30.
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| Sap30em1(IMPC)J | Whole-gene deletion | | mouse |
| Sap30tm1(NCOM)Cmhd | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |