Scamp5 | secretory carrier membrane protein 5

GeneMGI:1928948Synonyms: Sc5

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Mortality/aging Renal/urinary system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



hyperactivity	9 supporting datasets	Scamp5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.07x10^-23
abnormal behavior	1 supporting dataset	Scamp5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.66x10^-5
increased lean body mass	1 supporting dataset	Scamp5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.25x10^-5
decreased thigmotaxis	2 supporting datasets	Scamp5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.65x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Scamp5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.83x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Scamp5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal sleep behavior	1 supporting dataset	Scamp5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8.35x10^-5
increased urine microalbumin level	1 supporting dataset	Scamp5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	6.74x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Scamp5.

Associated images

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Histopathology

There is no histopathology data found for Scamp5.

IMPC related publications

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External links

No external links available for Scamp5.

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*Scamp5^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Scamp5^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Scamp5^{tm374539(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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