Ecrg4 | ECRG4 augurin precursor

GeneMGI:1926146Synonyms: augurin, 1500015O10Rik

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Skeleton Cardiovascular system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.13x10^-7
abnormal eye anterior chamber depth	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.06x10^-5
shortened QRS complex duration	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.75x10^-5
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.06x10^-6
increased body length	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.45x10^-7
increased circulating cholesterol level	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.02x10^-5
decreased large unstained cell number	1 supporting dataset	Ecrg4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.63x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ecrg4.

Associated images

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Histopathology

There is no histopathology data found for Ecrg4.

IMPC related publications

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External links

No external links available for Ecrg4.

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*Ecrg4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ecrg4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ecrg4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Ecrg4^{tm40480(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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