Ak7 | adenylate kinase 7
Physiological systems
24 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Cardiovascular system Mortality/aging
14 No significant impact
Data collections
Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged heart | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal thymus morphology | 2 supporting datasets | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| enlarged thymus | 2 supporting datasets | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| decreased circulating potassium level | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | 3.33x10-5 | ||
| abnormal testis morphology | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| small testis | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Ak7em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * |
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Human diseases caused by Ak7 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ak7.
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| Ak7em1(IMPC)Ccpcz | Exon Deletion | | mouse |