Scaper | S phase cyclin A-associated protein in the ER

GeneMGI:1925976Synonyms: D530014O03Rik, Zfp291

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetScapertm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased grip strength2 supporting datasetsScapertm1b(EUCOMM)HmguhomozygoteEarly adult2.02x10-6 
decreased blood urea nitrogen level1 supporting datasetScapertm1b(EUCOMM)HmguhomozygoteEarly adult9.83x10-5 
male infertility1 supporting datasetScapertm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Scapertm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Scapertm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Scapertm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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