Scaper | S phase cyclin A-associated protein in the ER
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Behavior/neurological Mortality/aging
14 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Scapertm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased grip strength | 2 supporting datasets | Scapertm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.02x10-6 | ||
| decreased blood urea nitrogen level | 1 supporting dataset | Scapertm1b(EUCOMM)Hmgu | homozygote | Early adult | 9.83x10-5 | ||
| male infertility | 1 supporting dataset | Scapertm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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Human diseases caused by Scaper mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Scaper.
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| Scapertm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Scapertm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Scapertm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |