Atrip | ATR interacting protein

GeneMGI:1925349Synonyms: 6620401K05Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetAtriptm1b(KOMP)WtsiheterozygoteEarly adult2.18x10-10 
increased circulating sodium level1 supporting datasetAtriptm1b(KOMP)WtsiheterozygoteEarly adult3.25x10-8 
embryonic lethality prior to organogenesis1 supporting datasetAtriptm1b(KOMP)WtsihomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetAtriptm1b(KOMP)WtsihomozygoteEarly adultN/A * 
increased circulating chloride level1 supporting datasetAtriptm1b(KOMP)WtsiheterozygoteEarly adult5.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

adrenal glandheterozygoteSection images
100% (2/2)0.7% (4/570)
aortaheterozygoteSection images
100% (2/2)0.19% (1/533)
brainheterozygoteSection images
100% (2/2)0.86% (5/579)
brainstemheterozygoteSection images
100% (2/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoteSection images
100% (2/2)0.22% (1/454)
cerebellumheterozygoteSection images
100% (2/2)0.56% (3/532)
cerebral cortexheterozygoteSection images
100% (2/2)0.41% (2/491)
epididymisheterozygoteSection images
100% (1/1)87.5% (21/24)
esophagusheterozygoteSection images
100% (2/2)1.67% (7/419)
Download adult data as:  
Rows per page: 

Human diseases caused by Atrip mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






Download data as:  

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Atriptm119157(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Atriptm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Atriptm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Atriptm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter