Hook1 | hook microtubule tethering protein 1
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Reproductive system Immune system Integument Hematopoietic system
13 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small spleen | 1 supporting dataset | Hook1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Hook1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Hook1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Hook1em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Hook1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Hook1.
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| Hook1em1(IMPC)Tcp | Exon Deletion | | mouse |
| Hook1tm88037(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |