Hook1 | hook microtubule tethering protein 1

GeneMGI:1925213Synonyms: azh, abnormal spermatozoon head shape, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Immune system Integument Hematopoietic system

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small spleen1 supporting datasetHook1em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetHook1em1(IMPC)TcphomozygoteEarly adultN/A * 
male infertility1 supporting datasetHook1em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetHook1em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hook1em1(IMPC)TcpExon Deletionmouse
Hook1tm88037(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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