Rab35 | RAB35, member RAS oncogene family

GeneMGI:1924657Synonyms: 9530019H02Rik, RAB1C, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



cataract	1 supporting dataset	Rab35^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.55x10^-5
abnormal lens morphology	1 supporting dataset	Rab35^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.85x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Rab35^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rab35.

Associated images

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Histopathology

There is no histopathology data found for Rab35.

IMPC related publications

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External links

No external links available for Rab35.

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*Rab35^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Rab35^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rab35^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rab35^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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