Coq8b | coenzyme Q8B
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Behavior/neurological Skeleton Mortality/aging
13 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| impaired glucose tolerance | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | heterozygote | Early adult | 9.21x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| decreased bone mineral content | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.62x10-5 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.32x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.91x10-10 | ||
| decreased locomotor activity | 1 supporting dataset | Coq8btm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.79x10-5 |
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External links
No external links available for Coq8b.
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| Coq8btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Coq8btm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |