Chd9 | chromodomain helicase DNA binding protein 9
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system
15 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased Langerhans cell number | 1 supporting dataset | Chd9tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| decreased circulating serum albumin level | 1 supporting dataset | Chd9tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.33x10-5 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Chd9tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.83x10-5 | ||
| decreased circulating amylase level | 1 supporting dataset | Chd9tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.3x10-8 |
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Human diseases caused by Chd9 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Chd9.
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| Chd9tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Chd9tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |