Elapor1 | endosome-lysosome associated apoptosis and autophagy regulator 1

GeneMGI:1923930Synonyms: Iir, Inceptor, +1 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Mortality/aging

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina vasculature morphology	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.57x10^-6
abnormal retina blood vessel morphology	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.44x10^-6
increased circulating glucose level	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.78x10^-5
increased fluid intake	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.12x10^-5
short tibia	2 supporting datasets	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.68x10^-7
abnormal vitreous body morphology	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.03x10^-6
decreased exploration in new environment	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.28x10^-10
preweaning lethality, incomplete penetrance	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased lymphocyte cell number	1 supporting dataset	Elapor1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.96x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Elapor1.

Associated images

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Histopathology

There is no histopathology data found for Elapor1.

IMPC related publications

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External links

No external links available for Elapor1.

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*Elapor1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Elapor1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Elapor1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Elapor1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Elapor1^{tm401(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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