Wdr38 | WD repeat domain 38
Physiological systems
13 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Behavior/neurological
10 No significant impact
11 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating calcium level | 1 supporting dataset | Wdr38em1(IMPC)J | homozygote | Early adult | 3.93x10-15 | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Wdr38em1(IMPC)J | homozygote | Early adult | 1.18x10-5 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Wdr38em1(IMPC)J | homozygote | Early adult | 2.07x10-5 | ||
| increased startle reflex | 1 supporting dataset | Wdr38em1(IMPC)J | homozygote | Early adult | 7.66x10-6 |
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Human diseases caused by Wdr38 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Wdr38.
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| Wdr38em1(IMPC)J | Exon Deletion | | mouse |
| Wdr38tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Wdr38tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |