Asb5 | ankyrin repeat and SOCs box-containing 5
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Endocrine/exocrine gland Hematopoietic system Skeleton
16 No significant impact
3 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal thymus morphology | 1 supporting dataset | Asb5em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal vertebrae morphology | 1 supporting dataset | Asb5em1(IMPC)Ccpcz | homozygote | Early adult | 5.39x10-5 | ||
| enlarged thymus | 1 supporting dataset | Asb5em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| decreased circulating sodium level | 1 supporting dataset | Asb5em1(IMPC)Ccpcz | homozygote | Early adult | 1.05x10-5 | ||
| increased circulating potassium level | 1 supporting dataset | Asb5em1(IMPC)Ccpcz | homozygote | Early adult | 5.86x10-5 |
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Human diseases caused by Asb5 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Asb5.
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| Asb5em1(IMPC)Ccpcz | Exon Deletion | | mouse |
| Asb5tm78114(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |